Vitamina B12
Methylcobalamin for vitamin supplementation research.
Certificate of Analysis included with every order.
Technical Specifications
| Purity | — |
|---|---|
| Form | Injectable solution |
| Storage | 2-8°C |
| Molecular Weight | 1355.37 Da |
| Sequence | Methylcobalamin |
| CAS Number | 68-19-9 |
About This Peptide
Vitamin B12 (Methylcobalamin) is an essential water-soluble vitamin involved in red blood cell formation, neurological function, and DNA synthesis. This injectable form provides the bioactive methylated version for optimal bioavailability research.
Research Applications
Vitamin B12 supplementation studies, methylation research, neurological function, red blood cell formation.
Mechanism of Action
Vitamin B12 (Methylcobalamin) is the bioactive, methylated form of cobalamin, an essential water-soluble vitamin required as a cofactor for two critical enzymatic reactions: methionine synthase (which converts homocysteine to methionine and is essential for DNA methylation) and methylmalonyl-CoA mutase (which is involved in fatty acid and amino acid metabolism). Methylcobalamin directly participates in the methyl transfer cycle, supporting SAM (S-adenosylmethionine) production, which is the universal methyl donor for epigenetic modifications, neurotransmitter synthesis, and phospholipid metabolism.
Research Applications
Methylcobalamin is used in research investigating one-carbon metabolism, DNA methylation patterns, homocysteine metabolism, and neurological function. Applications include studies of methylation cycle dynamics, neural myelination processes, red blood cell formation (erythropoiesis), and the relationship between B12 status and cognitive function. Researchers also employ injectable methylcobalamin in bioavailability studies comparing different cobalamin forms and in investigations of B12 deficiency-related neuropathology.
Storage & Handling Guidelines
Proper storage and handling are essential to maintain peptide integrity and ensure reliable research results. All Pepitiva Biolabs peptides are supplied as lyophilized (freeze-dried) powder, which provides excellent long-term stability when stored correctly. Store lyophilized peptides at -20°C for long-term storage or 2-8°C for short-term use. Once reconstituted, peptide solutions should be stored at 2-8°C and used within the timeframe specified in the product documentation. Always use sterile bacteriostatic water for reconstitution and handle peptides in a clean laboratory environment to prevent contamination. Avoid repeated freeze-thaw cycles, as thermal stress can cause peptide degradation and loss of biological activity.
Quality Control & Certification
This product is manufactured under strict quality control protocols and has been verified through comprehensive analytical testing. Each batch undergoes reverse-phase HPLC analysis for purity determination and electrospray ionization mass spectrometry (ESI-MS) for molecular identity confirmation. A detailed Certificate of Analysis (COA) is available for download, documenting purity percentage, molecular weight verification, appearance, and recommended storage conditions. Pepitiva Biolabs maintains batch-level traceability from synthesis through delivery, ensuring complete transparency and quality assurance for your research.
Frequently Asked Questions
Is this product approved for human use?
No. This product is intended exclusively for in vitro scientific research and laboratory use. It is not approved for human or veterinary use, not intended for diagnostic or therapeutic purposes, and should not be administered to humans or animals under any circumstances.
How do I reconstitute this peptide?
Add sterile bacteriostatic water slowly to the vial, directing the stream against the glass wall rather than directly onto the lyophilized powder. Gently swirl the vial until the powder is fully dissolved — do not shake vigorously. The recommended reconstitution volume depends on your desired concentration. Refer to the product documentation for specific guidance.
Can I get a Certificate of Analysis (COA)?
Yes. A Certificate of Analysis is included with every order and is also available for download from the product page. The COA documents HPLC purity, mass spectrometry identity confirmation, batch number, production date, and storage recommendations.
For research use only. Not for human consumption.
