The Healthy Hair, Skin & Nails Blend is a multi-ingredient research solution of B vitamins plus choline and inositol, supplied in a 10 mL sterile liquid vial and stored refrigerated. Despite the n...
The Healthy Hair, Skin & Nails Blend is a multi-ingredient research solution of B vitamins plus choline and inositol, supplied in a 10 mL sterile liquid vial and stored refrigerated. Despite the name used in some searches, it contains no peptides. The product specification lists:
Niacinamide (nicotinamide, vitamin B3) 50 mg
Thiamine HCl (vitamin B1) 50 mg
Pantothenic acid (vitamin B5) 25 mg
Choline 10 mg
Inositol 10 mg
Niacin (nicotinic acid, vitamin B3) 5 mg
Biotin (vitamin B7) 100 mcg
Folic acid (vitamin B9) 100 mcg
Riboflavin (vitamin B2) 100 mcg
What the evidence says about hair, skin and nails
Biotin is widely marketed for hair and nails, but a review of published cases found benefit only in people with an underlying deficiency or specific nail or hair disorders, and insufficient evidence for supplementation in healthy individuals.[4] A broader review concluded that the role of vitamins in hair loss is not entirely clear and that large placebo-controlled trials are needed.[5] We found no published study of this specific combination, and it is not an approved medicine.
For research use only. Not for human consumption.
Quality & Storage
≥98% purity. Sterile Liquid Vial. Storage: 2-8°C. For research purposes only.
Mechanism of Action
B vitamins as coenzymes
The eight B vitamins are water-soluble and act as coenzymes in a wide range of catabolic and anabolic reactions, supporting energy production, DNA and RNA synthesis and repair, and methylation.[1] The forms in this blend correspond to:
Thiamine (B1): precursor of thiamine pyrophosphate, a cofactor of pyruvate dehydrogenase and related enzymes.[1]
Riboflavin (B2): precursor of the flavin coenzymes FMN and FAD.[1]
Niacinamide and niacin (B3): precursors of NAD+ and NADP+ (see NAD+).[1]
Pantothenic acid (B5): building block of coenzyme A.[1]
Folic acid (B9): source of folate for one-carbon metabolism and methylation.[1]
Two forms of vitamin B3
Niacin (nicotinic acid) and niacinamide (nicotinamide) are both vitamin B3 but behave differently. Niacin activates the receptor GPR109A, which in mice mediated the skin flushing response through prostaglandin release from immune cells.[2] Nicotinamide is the form tested in a phase 3 trial in people with a history of non-melanoma skin cancer, where it lowered the rate of new skin cancers by 23% over 12 months compared with placebo.[3]
Choline and inositol
Choline and inositol are included alongside the B vitamins. They are not B vitamins themselves.
Research Applications
Laboratory research applications
Cell culture supplementation: defined B-vitamin backgrounds for keratinocyte, fibroblast or hair follicle cell studies.
Coenzyme metabolism: NAD, FAD and coenzyme A-dependent pathways.[1]
Vitamin B3 forms: comparing nicotinic acid and nicotinamide signaling.[2][3]
Note for assay design
Biotin interferes with immunoassays that use biotin-streptavidin binding. In healthy adults taking supplemental biotin, 9 of 23 biotinylated assays gave falsely high or falsely low results, while non-biotinylated assays were unaffected.[6] Samples exposed to this blend should be tested with that in mind.
This product is sold for laboratory research only and is not intended for human or veterinary use.
Storage & Handling Guidelines
Proper storage and handling are essential to maintain peptide integrity and ensure reliable research results. All Pepitiva Biolabs peptides are supplied as lyophilized (freeze-dried) powder, which provides excellent long-term stability when stored correctly. Store lyophilized peptides at -20°C for long-term storage or 2-8°C for short-term use. Once reconstituted, peptide solutions should be stored at 2-8°C and used within the timeframe specified in the product documentation. Always use sterile bacteriostatic water for reconstitution and handle peptides in a clean laboratory environment to prevent contamination. Avoid repeated freeze-thaw cycles, as thermal stress can cause peptide degradation and loss of biological activity.
Quality Control & Certification
This product is manufactured under strict quality control protocols and has been verified through comprehensive analytical testing. Each batch undergoes reverse-phase HPLC analysis for purity determination and electrospray ionization mass spectrometry (ESI-MS) for molecular identity confirmation. A detailed Certificate of Analysis (COA) is available for download, documenting purity percentage, molecular weight verification, appearance, and recommended storage conditions. Pepitiva Biolabs maintains batch-level traceability from synthesis through delivery, ensuring complete transparency and quality assurance for your research.
Frequently Asked Questions
What is in the Healthy Hair, Skin and Nails Blend?
Niacinamide 50 mg, thiamine HCl 50 mg, pantothenic acid 25 mg, choline 10 mg, inositol 10 mg, niacin 5 mg, biotin 100 mcg, folic acid 100 mcg and riboflavin 100 mcg, as listed in the product specification, in a 10 mL sterile solution.
Is the Healthy Hair, Skin and Nails Blend a peptide?
No. It is a vitamin solution (B vitamins plus choline and inositol). It contains no peptides.
Does biotin help hair and nail growth?
Published evidence supports benefit mainly when there is a biotin deficiency or a specific hair or nail disorder. A review found insufficient evidence for biotin supplementation in healthy individuals.
Why does the blend contain both niacin and niacinamide?
Both are forms of vitamin B3 and precursors of NAD+, but they act differently: niacin activates the GPR109A receptor, which causes flushing, while nicotinamide is the form studied in skin research.
Can biotin affect laboratory tests?
Yes. Biotin can interfere with immunoassays based on biotin-streptavidin binding, producing falsely high or falsely low results in some assays.
How should the blend be stored?
Keep the vial refrigerated at 2 to 8 °C.
Is this product approved for human use?
No. This product is intended exclusively for in vitro scientific research and laboratory use. It is not approved for human or veterinary use, not intended for diagnostic or therapeutic purposes, and should not be administered to humans or animals under any circumstances.
How do I reconstitute this peptide?
Add sterile bacteriostatic water slowly to the vial, directing the stream against the glass wall rather than directly onto the lyophilized powder. Gently swirl the vial until the powder is fully dissolved — do not shake vigorously. The recommended reconstitution volume depends on your desired concentration. Refer to the product documentation for specific guidance.
Can I get a Certificate of Analysis (COA)?
Yes. A Certificate of Analysis is included with every order and is also available for download from the product page. The COA documents HPLC purity, mass spectrometry identity confirmation, batch number, production date, and storage recommendations.
Scientific References
Kennedy DO. B Vitamins and the Brain: Mechanisms, Dose and Efficacy--A Review. Nutrients. 2016;8(2):68. PubMed
Benyó Z, Gille A, Kero J, et al. GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing. J Clin Invest. 2005;115(12):3634-3640. PubMed
Chen AC, Martin AJ, Choy B, et al. A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention. N Engl J Med. 2015;373(17):1618-1626. PubMed
Patel DP, Swink SM, Castelo-Soccio L. A Review of the Use of Biotin for Hair Loss. Skin Appendage Disord. 2017;3(3):166-169. PubMed
Almohanna HM, Ahmed AA, Tsatalis JP, Tosti A. The Role of Vitamins and Minerals in Hair Loss: A Review. Dermatol Ther (Heidelb). 2019;9(1):51-70. PubMed
Li D, Radulescu A, Shrestha RT, et al. Association of Biotin Ingestion With Performance of Hormone and Nonhormone Assays in Healthy Adults. JAMA. 2017;318(12):1150-1160. PubMed
Sources are peer-reviewed publications indexed in PubMed and trial registrations on ClinicalTrials.gov. Each citation was checked against its PubMed record.
For research use only. Not for human consumption.
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