AOD-9604
GH fragment for lipid metabolism research.
Certificate of Analysis included with every order.
Technical Specifications
| Purity | ≥98% |
|---|---|
| Form | Lyophilized powder |
| Storage | -20°C |
| Molecular Weight | 1815.08 Da |
| Sequence | YLRIVQCRSVEGSCGF |
| CAS Number | 221231-10-3 |
About This Peptide
AOD-9604 is a modified fragment of human growth hormone (hGH fragment 177-191). Unlike full-length hGH, AOD-9604 specifically targets lipid metabolism pathways without affecting IGF-1 levels or insulin sensitivity, making it a valuable tool for targeted metabolic research.
Research Applications
Lipid metabolism, fat oxidation pathways, hGH fragment studies, targeted metabolic research without IGF-1 effects.
Mechanism of Action
AOD-9604 is a modified fragment of human growth hormone (hGH), specifically comprising amino acids 177-191 of the hGH polypeptide chain. This synthetic peptide fragment retains the lipolytic (fat-metabolizing) activity of growth hormone while lacking its growth-promoting and diabetogenic effects. AOD-9604 stimulates lipolysis (the breakdown of fat) and inhibits lipogenesis (the formation of new fat) through mechanisms that involve beta-3 adrenergic receptor pathways and calcium-dependent signaling in adipose tissue, without affecting IGF-1 levels, blood glucose, or tissue growth.
Research Applications
AOD-9604 is utilized in research focused on lipid metabolism, adipose tissue biology, and growth hormone fragment pharmacology. Key research applications include studies of lipolysis and lipogenesis regulation, adipocyte signaling pathways, beta-3 adrenergic receptor mechanisms in fat tissue, and comparative analysis of growth hormone fragments versus full-length growth hormone. Researchers also employ AOD-9604 in investigations of cartilage repair mechanisms and osteoarthritis pathways, as the peptide has demonstrated chondroprotective properties in preclinical models.
Storage & Handling Guidelines
Proper storage and handling are essential to maintain peptide integrity and ensure reliable research results. All Pepitiva Biolabs peptides are supplied as lyophilized (freeze-dried) powder, which provides excellent long-term stability when stored correctly. Store lyophilized peptides at -20°C for long-term storage or 2-8°C for short-term use. Once reconstituted, peptide solutions should be stored at 2-8°C and used within the timeframe specified in the product documentation. Always use sterile bacteriostatic water for reconstitution and handle peptides in a clean laboratory environment to prevent contamination. Avoid repeated freeze-thaw cycles, as thermal stress can cause peptide degradation and loss of biological activity.
Quality Control & Certification
This product is manufactured under strict quality control protocols and has been verified through comprehensive analytical testing. Each batch undergoes reverse-phase HPLC analysis for purity determination and electrospray ionization mass spectrometry (ESI-MS) for molecular identity confirmation. A detailed Certificate of Analysis (COA) is available for download, documenting purity percentage, molecular weight verification, appearance, and recommended storage conditions. Pepitiva Biolabs maintains batch-level traceability from synthesis through delivery, ensuring complete transparency and quality assurance for your research.
Frequently Asked Questions
Is this product approved for human use?
No. This product is intended exclusively for in vitro scientific research and laboratory use. It is not approved for human or veterinary use, not intended for diagnostic or therapeutic purposes, and should not be administered to humans or animals under any circumstances.
How do I reconstitute this peptide?
Add sterile bacteriostatic water slowly to the vial, directing the stream against the glass wall rather than directly onto the lyophilized powder. Gently swirl the vial until the powder is fully dissolved — do not shake vigorously. The recommended reconstitution volume depends on your desired concentration. Refer to the product documentation for specific guidance.
Can I get a Certificate of Analysis (COA)?
Yes. A Certificate of Analysis is included with every order and is also available for download from the product page. The COA documents HPLC purity, mass spectrometry identity confirmation, batch number, production date, and storage recommendations.
For research use only. Not for human consumption.